The Distillery District is an historic and entertainment precinct located east of Downtown Toronto. It contains numerous cafes, restaurants and shops housed within heritage buildings of the former Gooderham and Worts Distillery. The 13-acre (52,000 sq. m) district comprises more than 40 heritage buildings and 10 streets, and is the largest collection of Victorian era industrial architecture in North America.

The Gooderham and Worts Distillery was founded in 1832, and by the late 1860s was the largest distillery in the world. Once providing over 2 million gallons of whisky, mostly for export on the world market, the company was bought out in later years by rival Hiram Walker Co., another large Canadian distiller. Its location on the side of the Canadian National Railway mainline and located at the mouth of the original route of the Don River outlet into Lake Ontario which facilitated transport connections to the rest of Canada and indeed the world, and the entire area was once the industrial centre of Toronto and transshipping hub.

With the de-industrialization of the surrounding area in the late 20th century, and the winding-down of the distillery operations, the district was left increasingly derelict. Surrounding industrial and commercial buildings and structures were often demolished, leaving the former distillery surrounded primarily by empty lots. Nonetheless, the closing of the remaining distillery operations in 1990 created redevelopment and investment opportunities for a district that contained the largest and best preserved collection of Victorian-era industrial architecture in North America.

The economic recession of the early 1990s, however, and the resulting crash in residential condominium prices and office lease rates in downtown Toronto, delayed efforts to revitalize the district. Nonetheless, two residential condominium buildings were constructed on the periphery of the district during the late 1990s.

While the site awaited redevelopment and reinvestment, the district's unique ambiance began to attract numerous film shoots. Since 1990, the site has served as a location for over 800 film and television productions.

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